Dr Christian Will See You Now is an eight-part series, set in a state-of-the-art clinic fitted with a fixed camera rig, that follows Jessen as he diagnoses, counsels and treats a variety of patients who need his help, in addition to supporting their loved ones too.
"We've all seen illnesses, but the affect they have on people and their partners and relationships is really quite profound, and can get really out of control," he says.
"It's the bit, I suppose, you think you can't talk to your doctor about, but actually, it should be what we do," insists the London-born medic. "And if we did manage that better, we would do better for our patients, and they would face their conditions very differently and more positively.
"The big revelation often in this show is [patients] come in with a medical problem that's really a manifestation of troubles within."
He recognises that shining a torch on mental health in such a way might raise eyebrows, however.
"There's no criticism of medicine there," he's quick to insist. "[But] I do have a criticism of the way the system makes us practice things.
"I have the luxury of time, which busy NHS doctors [don't]. How on earth can a GP possibly, in the eight minutes they have to see their patients, do the best for that patient? And that's not the fault of the GP, it's the fault of the system - this ridiculous system we've got. If I could change anything, it would be to give patients 20 minutes with their GPs, or longer."
Can he see that ever happening?
"We're our own worst enemy!" he exclaims, chuckling. "What really frustrates me is the way that you cannot criticise the NHS. It is a sacred, wonderful thing that must stay exactly the way it is, which is just perverse and will kill it.
"It needs radically to be overhauled and changed, but you're not allowed to do that and if I say anything vaguely critical, there's the whole social media..." he notes, shaking his head.
"I don't have a 'Save our NHS' badge on my Twitter page on purpose, because I actually think while the sentiment's great, the end point is frightening."
Celebrities using their starry status to speak out on delicate issues could also spell disaster, he reasons.
"You need to be aware of what you don't know - and not enough people are," quips the academic, who graduated in 2000 from University College London, having trained in general medicine, infectious disease, travel medicine and sexual health/HIV.
"I'm going to name names and say someone like Gwyneth Paltrow, who writes utter guff on her ridiculous vaginal-steaming blog that is just painful to read! I wish she would stick to what she knows, which is a horrible slightly misogynistic and patronising thing to say, but it's also true!
"It's very damaging when the Jenny McCarthy's of this world say, 'Vaccines kill your kids', and suddenly we've got outbreaks of measles all over the world because of this sort of nonsense."
So what's next in the running, apart from hopefully less selfies?
"I'm a bit of a live life day-to-day... I'd like to continue as I am; I enjoy what I do and I'm in a happy place," he states.
"Clearly I'd like [Dr Christian Will See You Now] to do well, but it's not an ego thing - I was really proud of the massive noise Embarrassing Bodies made and I'm very aware of the controversies, but I'd like this to be the more grown-up next stage."
Dr Christian Will See You Now premieres on W on Wednesday, March 22 at 9pm - BT TV channel 311.